El modafinilo, Alertec, Modavigil, Provigil CAS 68693-11-8

El modafinilo, Alertec, Modavigil, Provigil CAS 68693-11-8

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El modafinilo, Alertec, Modavigil, Provigil CAS 68693-11-8 sistemática (IUPAC) Nombre: 2-benzhydrylsulfinylethanamide Los datos clínicos Los nombres comerciales Alertec, Modavigil, Modiodal, Provigil, Modalert SAIA / Drugs.com monografía MedlinePlus a602016 de datos de licencia de la FDA: enlace Embarazo categoría AU: B3 EEUU: C (riesgo no descartó) AU jurídica: S4 (Prescripción solamente) CA: Lista F Reino Unido: POM (la receta sólo) de Estados Unidos: la Lista IV dependencia responsabilidad psicológica: Muy baja física: Insignificante responsabilidad Adicción muy baja a las bajas vías de administración oral biodisponibilidad datos farmacocinéticos No determinado debido a la proteína de unión a la insolubilidad acuosa 62% ...

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Modafinil,Alertec,Modavigil,Provigil CAS 68693-11-8

Systematic (IUPAC) name:2-benzhydrylsulfinylethanamide Clinical data Trade names Alertec, Modavigil, Modiodal, Provigil, Modalert AHFS/Drugs.com monograph MedlinePlus a602016 Licence data US FDA:link Pregnancy category  AU: B3 US: C (Risk not ruled out) Legal status  AU: S4 (Prescription only) CA: Schedule F UK: POM (Prescription only) US: Schedule IV Dependence liability Psychological: Very low Physical: Negligible Addiction liability Very low to low Routes of administration Oral Pharmacokinetic data Bioavailability Not determined due to the aqueous insolubility Protein binding 62% Metabolism Hepatic (primarily via amide hydrolysis;CYP1A2, CYP3A4, and CYP2B6) Biological half-life 15 hours (R-enantiomer), 4 hours (S-enantiomer) Excretion Urine (80%) Identifiers CAS Number 68693-11-8 Yes ATC code N06BA07 PubChem CID: 4236 IUPHAR/BPS 7555 DrugBank DB00745 Yes ChemSpider 4088 Yes UNII R3UK8X3U3D Yes KEGG D01832 Yes ChEBI CHEBI:31859 ChEMBL CHEMBL1373 Yes Chemical data Formula C15H15NO2S Molecular mass 273.35 g/mol

Modafinil is a wakefulness-promoting agent (or eugeroic) used for treatment of disorders such as narcolepsy, shift work sleep disorder, and excessive daytime sleepiness associated with obstructive sleep apnea. It has also seen widespread off-label use as a purported cognition-enhancing agent. In English-speaking countries it is sold under the brand names Alertec, Modavigil, and Provigil. In the United States modafinil is classified as a schedule IV controlled substance and restricted in availability and usage, due to concerns about possible addiction potential. In most other countries it is a prescription drug but not otherwise legally restricted.