U-47700 CAS 121348-98-9

U-47700 CAS 121348-98-9

Shot Description:

U-47700 CAS 121348-98-9 U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s. U-47700 was derived from an earlier opioid AH-7921. U-47700 is selective for the μ-opioid receptor, having around 7.5 x the potency of morphine in animal models. U-47700 is the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. The team looked for the key moieties which…

Inquiry Now

INQUIRY DETAILS *

INQUIRY DETAILS
  • captcha

Description:

U-47700 CAS 121348-98-9

U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s. U-47700 was derived from an earlier opioid AH-7921. U-47700 is selective for the μ-opioid receptor, having around 7.5 x the potency of morphine in animal models.

U-47700 is the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. The team looked for the key moieties which gave the greatest activity. Upjohn posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-47700 was the most active.


Tags: