Nitromethaqualone CAS 340-52-3

Nitromethaqualone CAS 340-52-3

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Nitromethaqualone CAS 340-52-3 Nitromethaqualone是具有类似镇静催眠properties.It安眠酮的类似物是显著更有效(10倍)相比母体化合物; 典型的剂量为约25 mg.However,芳族硝基代谢成相应的苯胺,这被证明是一个mutagen.As结果,nitromethaqualone没有进一步发展,由于毒性的担忧。

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Nitromethaqualone

Nitromethaqualone CAS 340-52-3

Nitromethaqualone is an analogue of methaqualone that has similar sedative and hypnotic properties.It is significantly more potent (10x) compared to the parent compound; the typical dose is approximately 25 mg.However, the aromatic nitro group is metabolised to the corresponding aniline, which proved to be a mutagen.As a consequence, nitromethaqualone was not developed further due to toxicity concerns.

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